BDBM50129233 3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 4-tert-butyl ester 2-furan-2-ylmethyl ester::CHEMBL63161

SMILES: Cc1c(c[nH]c1C(=O)OCc1ccco1)C(=O)OC(C)(C)C

InChI Key: InChIKey=ZDZFHCROROHMQL-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129233   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor (RAT)	BDBM50129233 (3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 4-tert-b...) Show SMILES Cc1c(c[nH]c1C(=O)OCc1ccco1)C(=O)OC(C)(C)C Show InChI InChI=1S/C16H19NO5/c1-10-12(14(18)22-16(2,3)4)8-17-13(10)15(19)21-9-11-6-5-7-20-11/h5-8,17H,9H2,1-4H3	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
GlaxoSmithKline Medicine Research Centre Curated by ChEMBL					Assay Description In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.				Bioorg Med Chem Lett 13: 2113-8 (2003) BindingDB Entry DOI: 10.7270/Q2PN9519
					More data for this Ligand-Target Pair