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BDBM50129239 3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-(2-dimethylamino-1-methyl-ethyl) ester 4-(1,2,2-trimethyl-propyl) ester::CHEMBL67197

SMILES: CC(CN(C)C)OC(=O)c1[nH]cc(C(=O)OC(C)C(C)(C)C)c1C

InChI Key: InChIKey=UCHBPQLCXWYHTN-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129239   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Metabotropic glutamate receptor


(RAT)		BDBM50129239
PNG
(3-Methyl-1H-pyrrole-2,4-dicarboxylic acid 2-(2-dim...)
Show SMILES CC(CN(C)C)OC(=O)c1[nH]cc(C(=O)OC(C)C(C)(C)C)c1C
Show InChI InChI=1S/C18H30N2O4/c1-11(10-20(7)8)23-17(22)15-12(2)14(9-19-15)16(21)24-13(3)18(4,5)6/h9,11,13,19H,10H2,1-8H3
PDB

UniProtKB/SwissProt

GoogleScholar
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CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a 390n/an/an/an/an/an/a



GlaxoSmithKline Medicine Research Centre

Curated by ChEMBL


Assay Description
In vitro inhibition of rat metabotropic glutamate receptor 1 in CHO cells using the CDP-DAG accumulation method.

Bioorg Med Chem Lett 13: 2113-8 (2003)


BindingDB Entry DOI: 10.7270/Q2PN9519
More data for this
Ligand-Target Pair