BDBM50129435 CHEMBL71783::N-{4-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-but-2-ynyl}-benzamide

SMILES: Clc1cccc(N2CCN(CC#CCNC(=O)c3ccccc3)CC2)c1Cl

InChI Key: InChIKey=NZDBRYJVPWCALT-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129435   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50129435 (CHEMBL71783 | N-{4-[4-(2,3-Dichloro-phenyl)-pipera...) Show SMILES Clc1cccc(N2CCN(CC#CCNC(=O)c3ccccc3)CC2)c1Cl Show InChI InChI=1S/C21H21Cl2N3O/c22-18-9-6-10-19(20(18)23)26-15-13-25(14-16-26)12-5-4-11-24-21(27)17-7-2-1-3-8-17/h1-3,6-10H,11-16H2,(H,24,27)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	394	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Binding affinity towards rat Dopamine receptor D3 in Sf9 cells expressing in recombinant baculovirus (Bv) using [125I]-IABN as radioligand				Bioorg Med Chem Lett 13: 2179-83 (2003) BindingDB Entry DOI: 10.7270/Q21Z43SN
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50129435 (CHEMBL71783 | N-{4-[4-(2,3-Dichloro-phenyl)-pipera...) Show SMILES Clc1cccc(N2CCN(CC#CCNC(=O)c3ccccc3)CC2)c1Cl Show InChI InChI=1S/C21H21Cl2N3O/c22-18-9-6-10-19(20(18)23)26-15-13-25(14-16-26)12-5-4-11-24-21(27)17-7-2-1-3-8-17/h1-3,6-10H,11-16H2,(H,24,27)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	1.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
National Institute on Drug Abuse-Intramural Research Program Curated by ChEMBL					Assay Description Binding affinity towards rat Dopamine receptor D2 in Sf9 cells expressing in recombinant baculovirus (Bv) using [125I]-IABN as radioligand				Bioorg Med Chem Lett 13: 2179-83 (2003) BindingDB Entry DOI: 10.7270/Q21Z43SN
					More data for this Ligand-Target Pair