BDBM50129512 CHEMBL304807::N-[4-[4-(1H-Benzoimidazol-2-yl)-piperidin-1-yl]-2-(3,4-dichloro-phenyl)-butyl]-N-methyl-benzamide

SMILES: CN(CC(CCN1CCC(CC1)c1nc2ccccc2[nH]1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1

InChI Key: InChIKey=KVWYIQSSLORAOG-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129512   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 2 receptor (Homo sapiens (Human))	BDBM50129512 (CHEMBL304807 | N-[4-[4-(1H-Benzoimidazol-2-yl)-pip...) Show SMILES CN(CC(CCN1CCC(CC1)c1nc2ccccc2[nH]1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 Show InChI InChI=1S/C30H32Cl2N4O/c1-35(30(37)22-7-3-2-4-8-22)20-24(23-11-12-25(31)26(32)19-23)15-18-36-16-13-21(14-17-36)29-33-27-9-5-6-10-28(27)34-29/h2-12,19,21,24H,13-18,20H2,1H3,(H,33,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	7.30	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligand				Bioorg Med Chem Lett 13: 2211-5 (2003) BindingDB Entry DOI: 10.7270/Q2D799TN
					More data for this Ligand-Target Pair