BDBM50129522 CHEMBL68917::N-[2-(3,4-Dichloro-phenyl)-4-(4-imidazol-1-yl-piperidin-1-yl)-butyl]-N-methyl-benzamide

SMILES: CN(CC(CCN1CCC(CC1)n1ccnc1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1

InChI Key: InChIKey=JCIUNIFVMIPOCX-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129522   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Neurokinin 2 receptor (Homo sapiens (Human))	BDBM50129522 (CHEMBL68917 | N-[2-(3,4-Dichloro-phenyl)-4-(4-imid...) Show SMILES CN(CC(CCN1CCC(CC1)n1ccnc1)c1ccc(Cl)c(Cl)c1)C(=O)c1ccccc1 Show InChI InChI=1S/C26H30Cl2N4O/c1-30(26(33)20-5-3-2-4-6-20)18-22(21-7-8-24(27)25(28)17-21)9-13-31-14-10-23(11-15-31)32-16-12-29-19-32/h2-8,12,16-17,19,22-23H,9-11,13-15,18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	7.70	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Global Research and Development Curated by ChEMBL					Assay Description Binding affinity for human tachykinin receptor 2 expressed in CHO cells using [125I]- NKA radioligand				Bioorg Med Chem Lett 13: 2211-5 (2003) BindingDB Entry DOI: 10.7270/Q2D799TN
					More data for this Ligand-Target Pair