BDBM50129535 5-(2',4'-Dichloro-biphenyl-4-yl)-1H-pyrazole-3-carboxylic acid::CHEMBL442177

SMILES: OC(=O)c1cc(n[nH]1)-c1ccc(cc1)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=SIKKXNVXBDJNHW-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129535   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Methionyl-tRNA synthetase (Homo sapiens (Human))	BDBM50129535 (5-(2',4'-Dichloro-biphenyl-4-yl)-1H-pyrazole-3-car...) Show SMILES OC(=O)c1cc(n[nH]1)-c1ccc(cc1)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C16H10Cl2N2O2/c17-11-5-6-12(13(18)7-11)9-1-3-10(4-2-9)14-8-15(16(21)22)20-19-14/h1-8H,(H,19,20)(H,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	3.28E+3	n/a	n/a	n/a	n/a	n/a	n/a
Cubist Pharmaceutical Inc. Curated by ChEMBL					Assay Description Inhibitory activity against Staphylococcus aureus methionyl-tRNA synthetase (SaMetRS)				Bioorg Med Chem Lett 13: 2231-4 (2003) BindingDB Entry DOI: 10.7270/Q24Q7TCM
					More data for this Ligand-Target Pair