BDBM50129683 2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmethyl]-4-methyl-pentanoic acid::CHEMBL2153736::CHEMBL328319::Diastereomer-2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmethyl]-4-methyl-pentanoic acid

SMILES: CC(C)CC(CP(O)(O)C(=N)CC(C)C)C(O)=O

InChI Key: InChIKey=FPDNRYGCFIRICC-UHFFFAOYSA-N

Data: 5 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50129683   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Leucine aminopeptidase (Homo sapiens (Human))	BDBM50129683 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...) Show SMILES CC(C)CC(CP(O)(O)C(=N)CC(C)C)C(O)=O Show InChI InChI=1S/C12H26NO4P/c1-8(2)5-10(12(14)15)7-18(16,17)11(13)6-9(3)4/h8-10,13,16-18H,5-7H2,1-4H3,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of LAP				J Med Chem 54: 5955-80 (2011) Article DOI: 10.1021/jm200587f BindingDB Entry DOI: 10.7270/Q2PV6MGF
					More data for this Ligand-Target Pair
Leucine aminopeptidase (Homo sapiens (Human))	BDBM50129683 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...) Show SMILES CC(C)CC(CP(O)(O)C(=N)CC(C)C)C(O)=O Show InChI InChI=1S/C12H26NO4P/c1-8(2)5-10(12(14)15)7-18(16,17)11(13)6-9(3)4/h8-10,13,16-18H,5-7H2,1-4H3,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	65	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
					More data for this Ligand-Target Pair
Leucine aminopeptidase (Homo sapiens (Human))	BDBM50129683 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...) Show SMILES CC(C)CC(CP(O)(O)C(=N)CC(C)C)C(O)=O Show InChI InChI=1S/C12H26NO4P/c1-8(2)5-10(12(14)15)7-18(16,17)11(13)6-9(3)4/h8-10,13,16-18H,5-7H2,1-4H3,(H,14,15)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	110	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity for cytosolic leucine aminopeptidase (LAP) from porcine kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
					More data for this Ligand-Target Pair
Aminopeptidase N (Sus scrofa (Pig))	BDBM50129683 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...) Show SMILES CC(C)CC(CP(O)(O)C(=N)CC(C)C)C(O)=O Show InChI InChI=1S/C12H26NO4P/c1-8(2)5-10(12(14)15)7-18(16,17)11(13)6-9(3)4/h8-10,13,16-18H,5-7H2,1-4H3,(H,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Binding affinity towards aminopeptidase N (APN) from pig kidney				J Med Chem 46: 2641-55 (2003) Article DOI: 10.1021/jm030795v BindingDB Entry DOI: 10.7270/Q27P903F
					More data for this Ligand-Target Pair
Aminopeptidase N (Homo sapiens (Human))	BDBM50129683 (2-[(1-Amino-3-methyl-butyl)-hydroxy-phosphinoylmet...) Show SMILES CC(C)CC(CP(O)(O)C(=N)CC(C)C)C(O)=O Show InChI InChI=1S/C12H26NO4P/c1-8(2)5-10(12(14)15)7-18(16,17)11(13)6-9(3)4/h8-10,13,16-18H,5-7H2,1-4H3,(H,14,15)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Wroclaw University of Technology Curated by ChEMBL					Assay Description Inhibition of APN				J Med Chem 54: 5955-80 (2011) Article DOI: 10.1021/jm200587f BindingDB Entry DOI: 10.7270/Q2PV6MGF
					More data for this Ligand-Target Pair