BDBM50129712 CHEMBL3628416

SMILES: CCOP(=O)(OCC)C(Nc1ccc(CNC(=O)C23CC4CC(CC(C4)C2)C3)cc1)c1ccncc1

InChI Key: InChIKey=ACHRCXPGUGQNPQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50129712 (CHEMBL3628416) Show SMILES CCOP(=O)(OCC)C(Nc1ccc(CNC(=O)C23CC4CC(CC(C4)C2)C3)cc1)c1ccncc1 |TLB:25:20:27:24.23.26,25:24:27:21.20.19,THB:16:18:21.20.25:23,19:18:21.20.25:23,19:20:23:18.27.26| Show InChI InChI=1S/C28H38N3O4P/c1-3-34-36(33,35-4-2)26(24-9-11-29-12-10-24)31-25-7-5-20(6-8-25)19-30-27(32)28-16-21-13-22(17-28)15-23(14-21)18-28/h5-12,21-23,26,31H,3-4,13-19H2,1-2H3,(H,30,32)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	185	n/a	n/a	n/a	n/a	n/a	n/a
Ehime University Curated by ChEMBL					Assay Description Inhibition of recombinant human sEH expressed in baculovirus infected insect Sf9 cells using CMNPC as substrate assessed as 6-methoxy-2-naphthadehyde...				Bioorg Med Chem 23: 7199-210 (2015) BindingDB Entry DOI: 10.7270/Q20P11VH
					More data for this Ligand-Target Pair