BDBM50129811 CHEMBL3628789

SMILES: COc1ccccc1OCCNC(=O)c1ccc(OC(F)F)c(OC2CCCC2)c1

InChI Key: InChIKey=ZDLZPHXFOZELTF-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129811   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphodiesterase 4 (Homo sapiens (Human))	BDBM50129811 (CHEMBL3628789) Show SMILES COc1ccccc1OCCNC(=O)c1ccc(OC(F)F)c(OC2CCCC2)c1 Show InChI InChI=1S/C22H25F2NO5/c1-27-17-8-4-5-9-18(17)28-13-12-25-21(26)15-10-11-19(30-22(23)24)20(14-15)29-16-6-2-3-7-16/h4-5,8-11,14,16,22H,2-3,6-7,12-13H2,1H3,(H,25,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.24E+4	n/a	n/a	n/a	n/a	n/a	n/a
Southern Medical University Curated by ChEMBL					Assay Description Inhibition of core catalytic domains of human PDE4 using AM-Cyclic-3',5'-AMP after 60 mins by fluorescence polarization assay				Bioorg Med Chem 23: 7332-9 (2015) BindingDB Entry DOI: 10.7270/Q2GQ70KG
					More data for this Ligand-Target Pair