BDBM50129826 CHEMBL3628794

SMILES: CCOC(=O)Nc1ccc(Nc2ncnc3sccc23)cc1C

InChI Key: InChIKey=ZIKVLGJYVJWPSD-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129826   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50129826 (CHEMBL3628794) Show SMILES CCOC(=O)Nc1ccc(Nc2ncnc3sccc23)cc1C Show InChI InChI=1S/C16H16N4O2S/c1-3-22-16(21)20-13-5-4-11(8-10(13)2)19-14-12-6-7-23-15(12)18-9-17-14/h4-9H,3H2,1-2H3,(H,20,21)(H,17,18,19)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR-2 after 1 hr using [gamma-32P]ATP				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50129826 (CHEMBL3628794) Show SMILES CCOC(=O)Nc1ccc(Nc2ncnc3sccc23)cc1C Show InChI InChI=1S/C16H16N4O2S/c1-3-22-16(21)20-13-5-4-11(8-10(13)2)19-14-12-6-7-23-15(12)18-9-17-14/h4-9H,3H2,1-2H3,(H,20,21)(H,17,18,19)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of human EGFR after 1 hr using [gamma-32P]ATP				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
					More data for this Ligand-Target Pair