null
SMILES: CCOC(=O)Nc1ccc(Nc2ncnc3sc4CCCCc4c23)cc1C
InChI Key: InChIKey=MLTVDTBSGMYDAA-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50129827 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Vascular endothelial growth factor receptor 2
(Homo sapiens (Human)) | BDBM50129827
(CHEMBL3628795)Show InChI InChI=1S/C20H22N4O2S/c1-3-26-20(25)24-15-9-8-13(10-12(15)2)23-18-17-14-6-4-5-7-16(14)27-19(17)22-11-21-18/h8-11H,3-7H2,1-2H3,(H,24,25)(H,21,22,23) | PDB MMDB
NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 3.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille
Curated by ChEMBL
| Assay Description Inhibition of human recombinant VEGFR-2 after 1 hr using [gamma-32P]ATP |
Bioorg Med Chem 23: 7340-7 (2015)
Article DOI: 10.1016/j.bmc.2015.10.035 BindingDB Entry DOI: 10.7270/Q2BZ67VR |
More data for this Ligand-Target Pair | |
Epidermal growth factor receptor
(Homo sapiens (Human)) | BDBM50129827
(CHEMBL3628795)Show InChI InChI=1S/C20H22N4O2S/c1-3-26-20(25)24-15-9-8-13(10-12(15)2)23-18-17-14-6-4-5-7-16(14)27-19(17)22-11-21-18/h8-11H,3-7H2,1-2H3,(H,24,25)(H,21,22,23) | PDB MMDB
KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Univ. Lille
Curated by ChEMBL
| Assay Description Inhibition of human EGFR after 1 hr using [gamma-32P]ATP |
Bioorg Med Chem 23: 7340-7 (2015)
Article DOI: 10.1016/j.bmc.2015.10.035 BindingDB Entry DOI: 10.7270/Q2BZ67VR |
More data for this Ligand-Target Pair | |