null

SMILES: CCOC(=O)Nc1ccc(Oc2ncnc3ccccc23)cc1C

InChI Key: InChIKey=DQBHWDLNZDTVBB-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50129836   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50129836 (CHEMBL3628804) Show SMILES CCOC(=O)Nc1ccc(Oc2ncnc3ccccc23)cc1C Show InChI InChI=1S/C18H17N3O3/c1-3-23-18(22)21-15-9-8-13(10-12(15)2)24-17-14-6-4-5-7-16(14)19-11-20-17/h4-11H,3H2,1-2H3,(H,21,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	710	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of human recombinant VEGFR-2 after 1 hr using [gamma-32P]ATP				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
					More data for this Ligand-Target Pair
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50129836 (CHEMBL3628804) Show SMILES CCOC(=O)Nc1ccc(Oc2ncnc3ccccc23)cc1C Show InChI InChI=1S/C18H17N3O3/c1-3-23-18(22)21-15-9-8-13(10-12(15)2)24-17-14-6-4-5-7-16(14)19-11-20-17/h4-11H,3H2,1-2H3,(H,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Univ. Lille Curated by ChEMBL					Assay Description Inhibition of human EGFR after 1 hr using [gamma-32P]ATP				Bioorg Med Chem 23: 7340-7 (2015) BindingDB Entry DOI: 10.7270/Q2BZ67VR
					More data for this Ligand-Target Pair