BDBM50129884 6-{4-[2-(2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-cyclohexylamino}-nicotinonitrile::CHEMBL94101

SMILES: O=C(CNC1CC[C@@H](CC1)Nc1ccc(cn1)C#N)N1CCC[C@H]1C#N

InChI Key: InChIKey=UYMWOBUVWMQNHM-BSOSBYQFSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129884   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50129884 (6-{4-[2-(2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino...) Show SMILES O=C(CNC1CC[C@@H](CC1)Nc1ccc(cn1)C#N)N1CCC[C@H]1C#N |wD:23.26,7.10,(9.43,3.59,;9.76,2.08,;8.61,1.04,;7.14,1.51,;6,.47,;6,-1.07,;4.67,-1.83,;3.34,-1.07,;3.34,.47,;4.67,1.25,;2.01,-1.83,;1.99,-3.37,;.66,-4.13,;.65,-5.67,;1.98,-6.45,;3.32,-5.68,;3.32,-4.14,;1.98,-7.99,;1.97,-9.53,;11.23,1.6,;11.71,.13,;13.25,.13,;13.73,1.6,;12.48,2.51,;13.24,3.85,;14,5.2,)| Show InChI InChI=1S/C19H24N6O/c20-10-14-3-8-18(23-12-14)24-16-6-4-15(5-7-16)22-13-19(26)25-9-1-2-17(25)11-21/h3,8,12,15-17,22H,1-2,4-7,9,13H2,(H,23,24)/t15?,16-,17-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cells				J Med Chem 46: 2774-89 (2003) Article DOI: 10.1021/jm030091l BindingDB Entry DOI: 10.7270/Q20001HR
					More data for this Ligand-Target Pair