BDBM50129902 6-{2-[2-(2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino]-2-methyl-propylamino}-nicotinonitrile::CHEMBL327166

SMILES: CC(C)(CNc1ccc(cn1)C#N)NCC(=O)N1CCC[C@H]1C#N

InChI Key: InChIKey=CPYUYVRELYDHIL-AWEZNQCLSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50129902   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM50129902 (6-{2-[2-(2-Cyano-pyrrolidin-1-yl)-2-oxo-ethylamino...) Show SMILES CC(C)(CNc1ccc(cn1)C#N)NCC(=O)N1CCC[C@H]1C#N Show InChI InChI=1S/C17H22N6O/c1-17(2,12-21-15-6-5-13(8-18)10-20-15)22-11-16(24)23-7-3-4-14(23)9-19/h5-6,10,14,22H,3-4,7,11-12H2,1-2H3,(H,20,21)/t14-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Novartis Institute for Biomedical Research Curated by ChEMBL					Assay Description Inhibition of human dipeptidyl peptidase IV (DPP IV) obtained from human colonic carcinoma cells				J Med Chem 46: 2774-89 (2003) Article DOI: 10.1021/jm030091l BindingDB Entry DOI: 10.7270/Q20001HR
					More data for this Ligand-Target Pair