BDBM50130066 2,2,2-Trifluoro-1-(2,3,4,5-tetrahydro-1H-[1,4]diazepino[1,7-a]indol-11-yl)-ethanone::CHEMBL310090

SMILES: FC(F)(F)C(=O)c1c2CCNCCn2c2ccccc12

InChI Key: InChIKey=WXYUSAFGLSPBAF-UHFFFAOYSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50130066   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2A (Homo sapiens (Human))	BDBM50130066 (2,2,2-Trifluoro-1-(2,3,4,5-tetrahydro-1H-[1,4]diaz...) Show SMILES FC(F)(F)C(=O)c1c2CCNCCn2c2ccccc12 Show InChI InChI=1S/C14H13F3N2O/c15-14(16,17)13(20)12-9-3-1-2-4-10(9)19-8-7-18-6-5-11(12)19/h1-4,18H,5-8H2	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand.				Bioorg Med Chem Lett 13: 2369-72 (2003) BindingDB Entry DOI: 10.7270/Q2B857GJ
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50130066 (2,2,2-Trifluoro-1-(2,3,4,5-tetrahydro-1H-[1,4]diaz...) Show SMILES FC(F)(F)C(=O)c1c2CCNCCn2c2ccccc12 Show InChI InChI=1S/C14H13F3N2O/c15-14(16,17)13(20)12-9-3-1-2-4-10(9)19-8-7-18-6-5-11(12)19/h1-4,18H,5-8H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	54	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Pharmacia Corporation Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand.				Bioorg Med Chem Lett 13: 2369-72 (2003) BindingDB Entry DOI: 10.7270/Q2B857GJ
					More data for this Ligand-Target Pair