BDBM50130091 9-Chloro-7-(5-chloro-2-methoxy-phenyl)-2,3,4,5,11,11a-hexahydro-1H-[1,4]diazepino[1,7-a]indole::CHEMBL310984
SMILES: COc1ccc(Cl)cc1-c1cc(Cl)cc2CC3CCNCCN3c12
InChI Key: InChIKey=USHJYIMZTIQJAK-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM50130091 (9-Chloro-7-(5-chloro-2-methoxy-phenyl)-2,3,4,5,11,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 756 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2A receptor using [125I]-DOI radioligand. | Bioorg Med Chem Lett 13: 2369-72 (2003) BindingDB Entry DOI: 10.7270/Q2B857GJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2C (Homo sapiens (Human)) | BDBM50130091 (9-Chloro-7-(5-chloro-2-methoxy-phenyl)-2,3,4,5,11,...) | Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 793 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pharmacia Corporation Curated by ChEMBL | Assay Description Binding affinity against 5-hydroxytryptamine 2C receptor using [125I]-DOI radioligand. | Bioorg Med Chem Lett 13: 2369-72 (2003) BindingDB Entry DOI: 10.7270/Q2B857GJ | |||||||||||
More data for this Ligand-Target Pair |