BDBM50130403 CHEMBL3633689
SMILES: CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3cc(ccc3-n3ccnn3)C(F)(F)F)cc2)cc[n+]1[O-]
InChI Key: InChIKey=DSGIFPOYMGNIQG-UHFFFAOYSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human)) | BDBM50130403 (CHEMBL3633689) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 49 | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ de Strasbourg Curated by ChEMBL | Assay Description Inhibition of GST-tagged human KDR expressed in Sf21 cells using 4:1 polyglutamic acid/tyrosine substrate incubated for 15 mins by scintillation coun... | Eur J Med Chem 103: 105-22 (2015) BindingDB Entry DOI: 10.7270/Q2P84DQG | |||||||||||
More data for this Ligand-Target Pair |