BDBM50130405 CHEMBL3633688

SMILES: Cc1cccc(NC(=O)Nc2ccc(cc2)-c2ccc3c(n[nH]c3c2)-c2cnn[nH]2)c1

InChI Key: InChIKey=UVZCZACZWWJXAZ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130405   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Vascular endothelial growth factor receptor 2 (Homo sapiens (Human))	BDBM50130405 (CHEMBL3633688) Show SMILES Cc1cccc(NC(=O)Nc2ccc(cc2)-c2ccc3c(n[nH]c3c2)-c2cnn[nH]2)c1 Show InChI InChI=1S/C23H19N7O/c1-14-3-2-4-18(11-14)26-23(31)25-17-8-5-15(6-9-17)16-7-10-19-20(12-16)27-29-22(19)21-13-24-30-28-21/h2-13H,1H3,(H,27,29)(H,24,28,30)(H2,25,26,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ de Strasbourg Curated by ChEMBL					Assay Description Inhibition of His6-tagged KDR 789 to 1354 residues (unknown origin) using biotin-Ahx-AEEEYFFLA-amide substrate incubated for 60 mins by HTRF assay				Eur J Med Chem 103: 105-22 (2015) BindingDB Entry DOI: 10.7270/Q2P84DQG
					More data for this Ligand-Target Pair