BDBM50130493 CHEMBL3633854

SMILES: CCc1cc(OC)ccc1-c1ccc(C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@](C)(Cc2c(F)cccc2F)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCCc2ccccc2)C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(O)=O)C(C)(C)S)C(C)(C)S)cc1

InChI Key: InChIKey=BZLFKKMHQPPZOI-ZAFIYQHQSA-N

Data: 1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130493   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucagon-like peptide 1 receptor (GLP-1) (Homo sapiens (Human))	BDBM50130493 (CHEMBL3633854) Show SMILES CCc1cc(OC)ccc1-c1ccc(C[C@H](NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CO)NC(=O)[C@@H](NC(=O)[C@](C)(Cc2c(F)cccc2F)NC(=O)[C@@H](NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H]2CCCN2C(=O)[C@@H](N)Cc2cnc[nH]2)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCCc2ccccc2)C(=O)N[C@H](C(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](C)C(=O)N[C@H](C(=O)N[C@@H](CO)C(O)=O)C(C)(C)S)C(C)(C)S)cc1 |r| Show InChI InChI=1S/C104H144F2N24O32S2/c1-13-58-37-61(162-12)31-32-62(58)59-29-27-57(28-30-59)36-69(91(150)119-67(25-17-22-56-20-15-14-16-21-56)90(149)128-84(102(7,8)163)97(156)114-44-76(137)111-46-77(138)116-52(3)87(146)118-51(2)86(145)112-43-75(136)109-42-74(135)110-45-78(139)117-53(4)88(147)127-85(103(9,10)164)98(157)124-72(49-132)100(159)160)121-92(151)70(39-81(143)144)122-93(152)71(48-131)123-95(154)82(54(5)133)126-101(161)104(11,40-63-64(105)23-18-24-65(63)106)129-96(155)83(55(6)134)125-79(140)47-113-89(148)68(33-34-80(141)142)120-94(153)73-26-19-35-130(73)99(158)66(107)38-60-41-108-50-115-60/h14-16,18,20-21,23-24,27-32,37,41,50-55,66-73,82-85,131-134,163-164H,13,17,19,22,25-26,33-36,38-40,42-49,107H2,1-12H3,(H,108,115)(H,109,136)(H,110,135)(H,111,137)(H,112,145)(H,113,148)(H,114,156)(H,116,138)(H,117,139)(H,118,146)(H,119,150)(H,120,153)(H,121,151)(H,122,152)(H,123,154)(H,124,157)(H,125,140)(H,126,161)(H,127,147)(H,128,149)(H,129,155)(H,141,142)(H,143,144)(H,159,160)/t51-,52-,53-,54+,55+,66-,67-,68-,69-,70-,71-,72-,73-,82-,83-,84+,85+,104-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	2.5	n/a	n/a	n/a	n/a
The University of Queensland Curated by ChEMBL					Assay Description Agonist activity at human GLP-1R expressed in CHO-K1 cells assessed as increase in cAMP level incubated for 30 mins				Eur J Med Chem 103: 175-84 (2015) BindingDB Entry DOI: 10.7270/Q2JH3P05
					More data for this Ligand-Target Pair