BDBM50130700 1-(5-Hydroxymethyl-bicyclo[3.1.0]hex-3-en-2-yl)-5-methyl-1H-pyrimidine-2,4-dione; triphosphate

SMILES: Cc1cn(C2C=C[C@]3(COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)C[C@H]23)c(=O)[nH]c1=O

InChI Key: InChIKey=JTFZQNJUWZQTAU-YKXYSFTHSA-J

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50130700   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Human immunodeficiency virus type 1 reverse transcriptase (Human immunodeficiency virus 1)	BDBM50130700 (1-(5-Hydroxymethyl-bicyclo[3.1.0]hex-3-en-2-yl)-5-...) Show SMILES Cc1cn(C2C=C[C@]3(COP([O-])(=O)OP([O-])(=O)OP([O-])([O-])=O)C[C@H]23)c(=O)[nH]c1=O |c:5| Show InChI InChI=1S/C12H17N2O12P3/c1-7-5-14(11(16)13-10(7)15)9-2-3-12(4-8(9)12)6-24-28(20,21)26-29(22,23)25-27(17,18)19/h2-3,5,8-9H,4,6H2,1H3,(H,20,21)(H,22,23)(H,13,15,16)(H2,17,18,19)/p-4/t8-,9?,12-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem	Article PubMed	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
National Cancer Institute-Frederick Curated by ChEMBL					Assay Description Inhibitory concentration required against Reverse transcriptase (RT)				J Med Chem 46: 3292-9 (2003) Article DOI: 10.1021/jm030116g BindingDB Entry DOI: 10.7270/Q2PR7WRP
					More data for this Ligand-Target Pair