BDBM50131011 8-Fluoro-2-(3-piperidin-1-yl-propionyl)-1,3,4,5-tetrahydro-2H-benzo[c][1,6]naphthyridin-6-one::8-fluoro-2-(3-(piperidin-1-yl)propanoyl)-1,2,3,4-tetrahydrobenzo[c][1,6]naphthyridin-6(5H)-one::8-fluoro-2-(3-piperidin-1-ylpropanoyl)-1,3,4,5-tetrahydrobenzo[c][1,6]naphthyridin-6(2H)-one::CHEMBL84096

SMILES: Fc1ccc2c3CN(CCc3[nH]c(=O)c2c1)C(=O)CCN1CCCCC1

InChI Key: InChIKey=CTOQXIXQHAILCA-UHFFFAOYSA-N

Data: 2 IC50

PDB links: 2 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50131011   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131011 (8-Fluoro-2-(3-piperidin-1-yl-propionyl)-1,3,4,5-te...) Show SMILES Fc1ccc2c3CN(CCc3[nH]c(=O)c2c1)C(=O)CCN1CCCCC1 Show InChI InChI=1S/C20H24FN3O2/c21-14-4-5-15-16(12-14)20(26)22-18-6-11-24(13-17(15)18)19(25)7-10-23-8-2-1-3-9-23/h4-5,12H,1-3,6-11,13H2,(H,22,26)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Johns Hopkins University Brain Science Institute Curated by ChEMBL					Assay Description Inhibition of PARP1				J Med Chem 53: 4561-84 (2010) Article DOI: 10.1021/jm100012m BindingDB Entry DOI: 10.7270/Q2NV9JF0
					More data for this Ligand-Target Pair
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM50131011 (8-Fluoro-2-(3-piperidin-1-yl-propionyl)-1,3,4,5-te...) Show SMILES Fc1ccc2c3CN(CCc3[nH]c(=O)c2c1)C(=O)CCN1CCCCC1 Show InChI InChI=1S/C20H24FN3O2/c21-14-4-5-15-16(12-14)20(26)22-18-6-11-24(13-17(15)18)19(25)7-10-23-8-2-1-3-9-23/h4-5,12H,1-3,6-11,13H2,(H,22,26)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Guilford Pharmaceuticals Inc. Curated by ChEMBL					Assay Description Inhibition of human recombinant Poly (ADP-ribose) polymerase 1				Bioorg Med Chem Lett 13: 2513-8 (2003) BindingDB Entry DOI: 10.7270/Q23N22S0
					More data for this Ligand-Target Pair