BDBM50131081 4-oxo-4H-chromene-3-carboxylic acid::CHEMBL315361

SMILES: OC(=O)c1coc2ccccc2c1=O

InChI Key: InChIKey=PCIITXGDSHXTSN-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131081   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein-tyrosine phosphatase 1B (Homo sapiens (Human))	BDBM50131081 (4-oxo-4H-chromene-3-carboxylic acid | CHEMBL315361) Show SMILES OC(=O)c1coc2ccccc2c1=O Show InChI InChI=1S/C10H6O4/c11-9-6-3-1-2-4-8(6)14-5-7(9)10(12)13/h1-5H,(H,12,13)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	PubMed	n/a	n/a	>1.00E+6	n/a	n/a	n/a	n/a	n/a	n/a
Inha University Curated by ChEMBL					Assay Description Inhibition of human Protein-tyrosine phosphatase 1B				Bioorg Med Chem Lett 13: 2561-3 (2003) BindingDB Entry DOI: 10.7270/Q2ZW1K9Q
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50131081 (4-oxo-4H-chromene-3-carboxylic acid | CHEMBL315361) Show SMILES OC(=O)c1coc2ccccc2c1=O Show InChI InChI=1S/C10H6O4/c11-9-6-3-1-2-4-8(6)14-5-7(9)10(12)13/h1-5H,(H,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	0.0480	n/a	n/a	n/a	n/a	n/a	n/a
Universidade do Porto Curated by ChEMBL					Assay Description Inhibition of human recombinant MAOB expressed in baculovirus-infected BTI insect cells after 15 mins by fluorimetric assay				Bioorg Med Chem Lett 21: 707-9 (2011) Article DOI: 10.1016/j.bmcl.2010.11.128 BindingDB Entry DOI: 10.7270/Q2ZW1M6S
					More data for this Ligand-Target Pair
Amine oxidase [flavin-containing] B (Homo sapiens (Human))	BDBM50131081 (4-oxo-4H-chromene-3-carboxylic acid | CHEMBL315361) Show SMILES OC(=O)c1coc2ccccc2c1=O Show InChI InChI=1S/C10H6O4/c11-9-6-3-1-2-4-8(6)14-5-7(9)10(12)13/h1-5H,(H,12,13)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ Magna Graecia di Catanzaro Curated by ChEMBL					Assay Description Inhibition of human recombinant MAO-B assessed as inhibition of production of hydrogen peroxide after 15 mins by the Amplex Red fluorimetric method				Bioorg Med Chem Lett 20: 2709-12 (2010) Article DOI: 10.1016/j.bmcl.2010.03.081 BindingDB Entry DOI: 10.7270/Q22V2G80
					More data for this Ligand-Target Pair