BDBM50131119 2-(6-Morpholin-4-ylmethyl-pyridin-2-ylamino)-benzothiazole-6-carboxylic acid (2-chloro-6-methyl-phenyl)-amide::CHEMBL86742

SMILES: Cc1cccc(Cl)c1NC(=O)c1ccc2nc(Nc3cccc(CN4CCOCC4)n3)sc2c1

InChI Key: InChIKey=JLLIWLGVLORBKA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131119   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50131119 (2-(6-Morpholin-4-ylmethyl-pyridin-2-ylamino)-benzo...) Show SMILES Cc1cccc(Cl)c1NC(=O)c1ccc2nc(Nc3cccc(CN4CCOCC4)n3)sc2c1 Show InChI InChI=1S/C25H24ClN5O2S/c1-16-4-2-6-19(26)23(16)30-24(32)17-8-9-20-21(14-17)34-25(28-20)29-22-7-3-5-18(27-22)15-31-10-12-33-13-11-31/h2-9,14H,10-13,15H2,1H3,(H,30,32)(H,27,28,29)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human p56 Lck tyrosine kinase				Bioorg Med Chem Lett 13: 2587-90 (2003) BindingDB Entry DOI: 10.7270/Q2FX78V4
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