BDBM50131127 2-(3,5-Dimethyl-pyridin-2-ylamino)-benzothiazole-6-carboxylic acid (2,4,6-trimethyl-phenyl)-amide::CHEMBL85295

SMILES: Cc1cnc(Nc2nc3ccc(cc3s2)C(=O)Nc2c(C)cc(C)cc2C)c(C)c1

InChI Key: InChIKey=JWJYTRLTTBQMEN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131127   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase Lck (Homo sapiens (Human))	BDBM50131127 (2-(3,5-Dimethyl-pyridin-2-ylamino)-benzothiazole-6...) Show SMILES Cc1cnc(Nc2nc3ccc(cc3s2)C(=O)Nc2c(C)cc(C)cc2C)c(C)c1 Show InChI InChI=1S/C24H24N4OS/c1-13-8-15(3)21(16(4)9-13)27-23(29)18-6-7-19-20(11-18)30-24(26-19)28-22-17(5)10-14(2)12-25-22/h6-12H,1-5H3,(H,27,29)(H,25,26,28)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Pharmaceutical Research Institute Curated by ChEMBL					Assay Description Inhibition of human p56 Lck tyrosine kinase				Bioorg Med Chem Lett 13: 2587-90 (2003) BindingDB Entry DOI: 10.7270/Q2FX78V4
					More data for this Ligand-Target Pair