BDBM50131381 (2R,3R,4R,5S)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,5-trihydroxy-piperidine-2-carboxylic acid hydroxyamide::CHEMBL93620
SMILES: ONC(=O)[C@H]1[C@@H](O)[C@H](O)[C@@H](O)CN1S(=O)(=O)c1ccc(OCc2ccccc2)cc1
InChI Key: InChIKey=LQZDEWIIFWHTLX-BSDSXHPESA-N
Data: 4 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Disintegrin and metalloproteinase domain-containing protein 17 (Homo sapiens (Human)) | BDBM50131381 ((2R,3R,4R,5S)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido Collaboration Center Curated by ChEMBL | Assay Description Inhibition of recombinant human TNF-alpha converting enzyme (TACE) | Bioorg Med Chem Lett 13: 2737-40 (2003) BindingDB Entry DOI: 10.7270/Q2PC31SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Stromelysin-1 (Homo sapiens (Human)) | BDBM50131381 ((2R,3R,4R,5S)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido Collaboration Center Curated by ChEMBL | Assay Description Inhibition of recombinant human matrix metalloproteinase-3 | Bioorg Med Chem Lett 13: 2737-40 (2003) BindingDB Entry DOI: 10.7270/Q2PC31SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Matrix metalloproteinase-9 (Homo sapiens (Human)) | BDBM50131381 ((2R,3R,4R,5S)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 6.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido Collaboration Center Curated by ChEMBL | Assay Description Inhibition of recombinant human matrix metalloproteinase-9 | Bioorg Med Chem Lett 13: 2737-40 (2003) BindingDB Entry DOI: 10.7270/Q2PC31SG | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Interstitial collagenase (Homo sapiens (Human)) | BDBM50131381 ((2R,3R,4R,5S)-1-(4-Benzyloxy-benzenesulfonyl)-3,4,...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 850 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Hokkaido Collaboration Center Curated by ChEMBL | Assay Description Inhibition of recombinant human matrix metalloproteinase-1 | Bioorg Med Chem Lett 13: 2737-40 (2003) BindingDB Entry DOI: 10.7270/Q2PC31SG | |||||||||||
More data for this Ligand-Target Pair |