BDBM50131431 2,3-Dihydro-1H-indole-3-carboxylic acid (3S,7S)-10-oxo-8-aza-tricyclo[5.3.1.0*3,8*]undec-5-yl ester::CHEMBL319742

SMILES: O=C(OC1C[C@@H]2CC3C[C@@H](C1)N2CC3=O)C1CNc2ccccc12

InChI Key: InChIKey=AUTMMRXGMHRYPS-OSBDVLARSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131431   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50131431 (2,3-Dihydro-1H-indole-3-carboxylic acid (3S,7S)-10...) Show SMILES O=C(OC1C[C@@H]2CC3C[C@@H](C1)N2CC3=O)C1CNc2ccccc12 |wD:9.11,5.12,TLB:14:13:5.6:9.8,12:11:3.4.10:7.6.8,(.12,-10.83,;.12,-9.28,;1.46,-8.5,;2.81,-9.27,;2.81,-10.81,;4.12,-11.58,;4.12,-10.04,;8.12,-9.28,;6.79,-8.5,;5.46,-9.27,;4.12,-8.5,;5.46,-10.81,;6.79,-11.58,;8.12,-10.83,;9.45,-11.6,;-1.21,-8.51,;-1.37,-6.97,;-2.89,-6.65,;-3.64,-7.98,;-5.14,-8.31,;-5.63,-9.77,;-4.58,-10.92,;-3.09,-10.59,;-2.61,-9.13,)| Show InChI InChI=1S/C19H22N2O3/c22-18-10-21-12-5-11(18)6-13(21)8-14(7-12)24-19(23)16-9-20-17-4-2-1-3-15(16)17/h1-4,11-14,16,20H,5-10H2/t11?,12-,13-,14?,16?/m0/s1	PDB MMDB Reactome pathway KEGG B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	PubMed	n/a	n/a	5.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Gedeon Richter Ltd Curated by ChEMBL					Assay Description Inhibition of human Potassium channel HERG expressed in mammalian cells				Bioorg Med Chem Lett 13: 2773-5 (2003) BindingDB Entry DOI: 10.7270/Q2QZ2BGZ
					More data for this Ligand-Target Pair