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BDBM50131722 4-(2-Fluoro-phenyl)-3-methyl-quinoline-2-carboxylic acid benzylamide::CHEMBL122301

SMILES: Cc1c(nc2ccccc2c1-c1ccccc1F)C(=O)NCc1ccccc1

InChI Key: InChIKey=ZAQVSWUKWOBQNH-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50131722   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Peripheral-Type Benzodiazepine Receptor


(Rattus norvegicus (rat))		BDBM50131722
PNG
(4-(2-Fluoro-phenyl)-3-methyl-quinoline-2-carboxyli...)
Show SMILES Cc1c(nc2ccccc2c1-c1ccccc1F)C(=O)NCc1ccccc1 |(9.69,-3.81,;8.36,-3.04,;8.35,-1.5,;7.01,-.73,;5.69,-1.52,;4.35,-.75,;3.02,-1.52,;3.02,-3.06,;4.35,-3.83,;5.69,-3.06,;7.03,-3.83,;7.03,-5.35,;5.69,-6.12,;5.69,-7.66,;7.03,-8.43,;8.36,-7.65,;8.36,-6.12,;9.69,-5.34,;9.68,-.72,;9.67,.82,;11.02,-1.48,;12.35,-.71,;13.68,-1.47,;15,-.68,;16.34,-1.45,;16.36,-2.99,;15.03,-3.76,;13.68,-3.01,)|
Show InChI InChI=1S/C24H19FN2O/c1-16-22(18-11-5-7-13-20(18)25)19-12-6-8-14-21(19)27-23(16)24(28)26-15-17-9-3-2-4-10-17/h2-14H,15H2,1H3,(H,26,28)
PDB

KEGG

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PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.49E+3n/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibitory activity against specific binding of [3H]-CB 34 to peripheral benzodiazepine receptor in rat cortical membranes was evaluated

J Med Chem 46: 3568-71 (2003)


Article DOI: 10.1021/jm034068b
BindingDB Entry DOI: 10.7270/Q2D79C5Z
More data for this
Ligand-Target Pair