BDBM50131935 CHEMBL126590::Pyrrolo[1,2-a]quinoxaline-4-carboxylic acid {4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-amide

SMILES: COc1ccccc1N1CCN(CCCCNC(=O)c2nc3ccccc3n3cccc23)CC1

InChI Key: InChIKey=KWGKDFPPFUUSKQ-UHFFFAOYSA-N

Data: 3 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50131935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Rattus norvegicus (Rat))	BDBM50131935 (CHEMBL126590 | Pyrrolo[1,2-a]quinoxaline-4-carboxy...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2nc3ccccc3n3cccc23)CC1 Show InChI InChI=1S/C27H31N5O2/c1-34-25-13-5-4-11-23(25)31-19-17-30(18-20-31)15-7-6-14-28-27(33)26-24-12-8-16-32(24)22-10-3-2-9-21(22)29-26/h2-5,8-13,16H,6-7,14-15,17-20H2,1H3,(H,28,33)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	28	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum Dopamine receptor D3 (sf9 cells) by [3H]7-OH-DPAT displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Rattus norvegicus (rat))	BDBM50131935 (CHEMBL126590 | Pyrrolo[1,2-a]quinoxaline-4-carboxy...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2nc3ccccc3n3cccc23)CC1 Show InChI InChI=1S/C27H31N5O2/c1-34-25-13-5-4-11-23(25)31-19-17-30(18-20-31)15-7-6-14-28-27(33)26-24-12-8-16-32(24)22-10-3-2-9-21(22)29-26/h2-5,8-13,16H,6-7,14-15,17-20H2,1H3,(H,28,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum Dopamine receptor D2 by [3H]spiperone displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair
D(1A) dopamine receptor (RAT)	BDBM50131935 (CHEMBL126590 | Pyrrolo[1,2-a]quinoxaline-4-carboxy...) Show SMILES COc1ccccc1N1CCN(CCCCNC(=O)c2nc3ccccc3n3cccc23)CC1 Show InChI InChI=1S/C27H31N5O2/c1-34-25-13-5-4-11-23(25)31-19-17-30(18-20-31)15-7-6-14-28-27(33)26-24-12-8-16-32(24)22-10-3-2-9-21(22)29-26/h2-5,8-13,16H,6-7,14-15,17-20H2,1H3,(H,28,33)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	778	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Siena Curated by ChEMBL					Assay Description Binding affinity for rat striatum dopamine Dopamine receptor D1 by [3H]-SCH- -2339 displacement.				J Med Chem 46: 3822-39 (2003) Article DOI: 10.1021/jm0211220 BindingDB Entry DOI: 10.7270/Q2H132RF
					More data for this Ligand-Target Pair