BDBM50132005 5-Methoxy-3-(4-oxo-2-thioxo-thiazolidin-5-ylidene)-1,3-dihydro-indol-2-one::5-methoxy-3-(4-oxo-2-thioxothiazolidin-5-ylidene)indolin-2-one::CHEMBL130414::CHEMBL362785

SMILES: COc1ccc2NC(=O)C(=C3SC(S)=NC3=O)c2c1

InChI Key: InChIKey=UTIFPSGFLVZWBR-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132005   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein kinase Pfmrk (Plasmodium falciparum)	BDBM50132005 (5-Methoxy-3-(4-oxo-2-thioxo-thiazolidin-5-ylidene)...) Show SMILES COc1ccc2NC(=O)C(=C3SC(S)=NC3=O)c2c1 |w:10.15,c:13| Show InChI InChI=1S/C12H8N2O3S2/c1-17-5-2-3-7-6(4-5)8(10(15)13-7)9-11(16)14-12(18)19-9/h2-4H,1H3,(H,13,15)(H,14,16,18)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
Walter Reed Army Institute of Research Curated by ChEMBL					Assay Description Inhibition of Plasmodium falciparum cyclin-dependent kinase				J Med Chem 47: 5418-26 (2004) Article DOI: 10.1021/jm040108f BindingDB Entry DOI: 10.7270/Q2BZ66TW
					More data for this Ligand-Target Pair
Protein kinase Pfmrk (Plasmodium falciparum)	BDBM50132005 (5-Methoxy-3-(4-oxo-2-thioxo-thiazolidin-5-ylidene)...) Show SMILES COc1ccc2NC(=O)C(=C3SC(S)=NC3=O)c2c1 |w:10.15,c:13| Show InChI InChI=1S/C12H8N2O3S2/c1-17-5-2-3-7-6(4-5)8(10(15)13-7)9-11(16)14-12(18)19-9/h2-4H,1H3,(H,13,15)(H,14,16,18)	UniProtKB/TrEMBL GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.71E+4	n/a	n/a	n/a	n/a	n/a	n/a
Institute of Research Curated by ChEMBL					Assay Description Inhibitory activity against Plasmodium falciparum cyclin dependent protein kinase, Pfmrk				J Med Chem 46: 3877-82 (2003) Article DOI: 10.1021/jm0300983 BindingDB Entry DOI: 10.7270/Q2028S9W
					More data for this Ligand-Target Pair