BDBM50132040 3-(4-Methoxy-phenyl)-N-{4-[4-(2-methoxy-phenyl)-piperazin-1-yl]-butyl}-acrylamide::CHEMBL127311

SMILES: COc1ccc(\C=C\C(=O)NCCCCN2CCN(CC2)c2ccccc2OC)cc1

InChI Key: InChIKey=PWYAMFWGADVMGC-SDNWHVSQSA-N

Data: 2 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132040   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
D(3) dopamine receptor (Homo sapiens (Human))	BDBM50132040 (3-(4-Methoxy-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pi...) Show SMILES COc1ccc(\C=C\C(=O)NCCCCN2CCN(CC2)c2ccccc2OC)cc1 Show InChI InChI=1S/C25H33N3O3/c1-30-22-12-9-21(10-13-22)11-14-25(29)26-15-5-6-16-27-17-19-28(20-18-27)23-7-3-4-8-24(23)31-2/h3-4,7-14H,5-6,15-20H2,1-2H3,(H,26,29)/b14-11+	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.380	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Binding affinity for human dopamine receptor D3 by displacing [125I]-iodosulpiride expressed in CHO cells				J Med Chem 46: 3883-99 (2003) Article DOI: 10.1021/jm030836n BindingDB Entry DOI: 10.7270/Q23F4P18
					More data for this Ligand-Target Pair
D(2) dopamine receptor (Homo sapiens (Human))	BDBM50132040 (3-(4-Methoxy-phenyl)-N-{4-[4-(2-methoxy-phenyl)-pi...) Show SMILES COc1ccc(\C=C\C(=O)NCCCCN2CCN(CC2)c2ccccc2OC)cc1 Show InChI InChI=1S/C25H33N3O3/c1-30-22-12-9-21(10-13-22)11-14-25(29)26-15-5-6-16-27-17-19-28(20-18-27)23-7-3-4-8-24(23)31-2/h3-4,7-14H,5-6,15-20H2,1-2H3,(H,26,29)/b14-11+	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Johann Wolfgang Goethe-Universität Curated by ChEMBL					Assay Description Binding affinity for human dopamine receptor D2 by displacing [125I]-iodosulpiride expressed in CHO cells				J Med Chem 46: 3883-99 (2003) Article DOI: 10.1021/jm030836n BindingDB Entry DOI: 10.7270/Q23F4P18
					More data for this Ligand-Target Pair