BDBM50132104 6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline::6-methoxy-harmalan::CHEMBL338115

SMILES: COc1ccc2[nH]c3c(CCN=C3C)c2c1

InChI Key: InChIKey=HMBHRMFLDKKSCT-UHFFFAOYSA-N

Data: 15 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50132104   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	924	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2C receptor				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	1.93E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 6 receptor				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	2.96E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 7 receptor				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
Sodium-dependent noradrenaline transporter (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>4.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards NET				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2A (Rattus norvegicus (rat))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	5.60E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 2A receptor				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1D (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1D receptor				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
SLC6A3 (BOVINE)	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards DAT (bovine)				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor (Rattus norvegicus-Rattus norvegicus (Rat)-RAT)	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards Alpha-2B adrenergic receptor				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
Dopamine receptor (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards cloned rat 5-hydroxytryptamine 2A receptor by [3H]-ketanserin displacement.				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1B (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1B receptor				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 1A (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards 5-hydroxytryptamine 1A receptor				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
Sodium-dependent serotonin transporter (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards Serotonin transporter				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
Muscarinic acetylcholine receptor (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia antibodypedia antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards Muscarinic acetylcholine receptor				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards human 5-hydroxytryptamine 5A receptor using LSD as radioligand				J Med Chem 46: 3930-7 (2003) Article DOI: 10.1021/jm030080s BindingDB Entry DOI: 10.7270/Q2V1245C
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 5A (Homo sapiens (Human))	BDBM50132104 (6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline |...) Show SMILES COc1ccc2[nH]c3c(CCN=C3C)c2c1 |c:11| Show InChI InChI=1S/C13H14N2O/c1-8-13-10(5-6-14-8)11-7-9(16-2)3-4-12(11)15-13/h3-4,7,15H,5-6H2,1-2H3	KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Virginia Commonwealth University Curated by ChEMBL					Assay Description Binding affinity towards 5-HT5A receptor				Bioorg Med Chem Lett 13: 4421-5 (2003) BindingDB Entry DOI: 10.7270/Q2D21X2G
					More data for this Ligand-Target Pair