BDBM50132226 4-(7-Chloro-6-nitro-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-phenoxy-phenyl)-amide::CHEMBL430849

SMILES: [O-][N+](=O)c1cc2c(ncnc2cc1Cl)N1CCN(CC1)C(=O)Nc1ccc(Oc2ccccc2)cc1

InChI Key: InChIKey=QCGJNSJMSPESJH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132226   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50132226 (4-(7-Chloro-6-nitro-quinazolin-4-yl)-piperazine-1-...) Show SMILES [O-][N+](=O)c1cc2c(ncnc2cc1Cl)N1CCN(CC1)C(=O)Nc1ccc(Oc2ccccc2)cc1 Show InChI InChI=1S/C25H21ClN6O4/c26-21-15-22-20(14-23(21)32(34)35)24(28-16-27-22)30-10-12-31(13-11-30)25(33)29-17-6-8-19(9-7-17)36-18-4-2-1-3-5-18/h1-9,14-16H,10-13H2,(H,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory concentration against platelet-derived growth factor receptor beta phosphorylation in CHO cells				Bioorg Med Chem Lett 13: 3001-4 (2003) BindingDB Entry DOI: 10.7270/Q2668CKR
					More data for this Ligand-Target Pair