BDBM50132231 4-(7-Chloro-quinazolin-4-yl)-piperazine-1-carbothioic acid benzylamide::CHEMBL100852

SMILES: Clc1ccc2c(ncnc2c1)N1CCN(CC1)C(=S)NCc1ccccc1

InChI Key: InChIKey=UKIUFHVXOQAYIT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132231   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Platelet-derived growth factor receptor beta (Homo sapiens (Human))	BDBM50132231 (4-(7-Chloro-quinazolin-4-yl)-piperazine-1-carbothi...) Show SMILES Clc1ccc2c(ncnc2c1)N1CCN(CC1)C(=S)NCc1ccccc1 Show InChI InChI=1S/C20H20ClN5S/c21-16-6-7-17-18(12-16)23-14-24-19(17)25-8-10-26(11-9-25)20(27)22-13-15-4-2-1-3-5-15/h1-7,12,14H,8-11,13H2,(H,22,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
Kyowa Hakko Kogyo Co., Ltd. Curated by ChEMBL					Assay Description Inhibitory concentration against platelet-derived growth factor receptor beta phosphorylation in CHO cells				Bioorg Med Chem Lett 13: 3001-4 (2003) BindingDB Entry DOI: 10.7270/Q2668CKR
					More data for this Ligand-Target Pair