BDBM50132405 5-(6,7-Dimethoxy-quinoxalin-2-ylamino)-bicyclo[2.2.1]heptan-2-ol::CHEMBL105322
SMILES: COc1cc2ncc(N[C@@H]3CC4CC3C[C@H]4O)nc2cc1OC
InChI Key: InChIKey=FIQQIMWSRXTHTA-BXTUAPDASA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
PDGFR-beta/Platelet-derived growth factor receptor alpha (Homo sapiens (Human)) | BDBM50132405 (5-(6,7-Dimethoxy-quinoxalin-2-ylamino)-bicyclo[2.2...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Aventis Pharmaceuticals Curated by ChEMBL | Assay Description Inhibition of Platelet-derived growth factor receptor | Bioorg Med Chem Lett 13: 3097-100 (2003) BindingDB Entry DOI: 10.7270/Q2HH6JGM | |||||||||||
More data for this Ligand-Target Pair |