BDBM50132791 CHEMBL3634451

SMILES: Cc1ccoc1C(=O)Nc1ncc(cn1)N1C(=O)c2ccccc2C1=O

InChI Key: InChIKey=HKENFXOVRHUQKC-UHFFFAOYSA-N

Data: 1 IC50  2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50132791   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50132791 (CHEMBL3634451) Show SMILES Cc1ccoc1C(=O)Nc1ncc(cn1)N1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C18H12N4O4/c1-10-6-7-26-14(10)15(23)21-18-19-8-11(9-20-18)22-16(24)12-4-2-3-5-13(12)17(22)25/h2-9H,1H3,(H,19,20,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Inhibition of bovine trypsin				Bioorg Med Chem Lett 25: 5107-10 (2015) BindingDB Entry DOI: 10.7270/Q20C4XKQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 1 (Homo sapiens (Human))	BDBM50132791 (CHEMBL3634451) Show SMILES Cc1ccoc1C(=O)Nc1ncc(cn1)N1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C18H12N4O4/c1-10-6-7-26-14(10)15(23)21-18-19-8-11(9-20-18)22-16(24)12-4-2-3-5-13(12)17(22)25/h2-9H,1H3,(H,19,20,21,23)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR1 by calcium mobilization assay				Bioorg Med Chem Lett 25: 5107-10 (2015) BindingDB Entry DOI: 10.7270/Q20C4XKQ
					More data for this Ligand-Target Pair
Metabotropic glutamate receptor 4 (mGluR4) (Homo sapiens (Human))	BDBM50132791 (CHEMBL3634451) Show SMILES Cc1ccoc1C(=O)Nc1ncc(cn1)N1C(=O)c2ccccc2C1=O Show InChI InChI=1S/C18H12N4O4/c1-10-6-7-26-14(10)15(23)21-18-19-8-11(9-20-18)22-16(24)12-4-2-3-5-13(12)17(22)25/h2-9H,1H3,(H,19,20,21,23)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Vanderbilt University Medical Center Curated by ChEMBL					Assay Description Positive allosteric modulation of human mGluR4 by calcium mobilization assay				Bioorg Med Chem Lett 25: 5107-10 (2015) BindingDB Entry DOI: 10.7270/Q20C4XKQ
					More data for this Ligand-Target Pair