BDBM50132820 CHEMBL3634556

SMILES: Fc1cc(COc2ccn3c(cnc3n2)-c2cncnc2)cc(F)c1Oc1cccc(c1)C(F)(F)F

InChI Key: InChIKey=JCBMPCBZNPHWIB-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132820   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
LDL-associated phospholipase A2 (Homo sapiens (Human))	BDBM50132820 (CHEMBL3634556) Show SMILES Fc1cc(COc2ccn3c(cnc3n2)-c2cncnc2)cc(F)c1Oc1cccc(c1)C(F)(F)F Show InChI InChI=1S/C24H14F5N5O2/c25-18-6-14(7-19(26)22(18)36-17-3-1-2-16(8-17)24(27,28)29)12-35-21-4-5-34-20(11-32-23(34)33-21)15-9-30-13-31-10-15/h1-11,13H,12H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Chinese Academy of Sciences Curated by ChEMBL					Assay Description Inhibition of recombinant human Lp-PLA2 using 2-thio-PAF substrate after 10 mins				J Med Chem 58: 8529-41 (2015) BindingDB Entry DOI: 10.7270/Q2VQ34H4
					More data for this Ligand-Target Pair