BDBM50132902 CHEMBL114861::Dibutyl-[3-(2,4-dichloro-phenyl)-1-ethyl-5-methyl-1H-pyrazolo[4,3-b]pyridin-7-yl]-amine

SMILES: CCCCN(CCCC)c1cc(C)nc2c(nn(CC)c12)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=CDTWBJRLECMRNA-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132902   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132902 (CHEMBL114861 | Dibutyl-[3-(2,4-dichloro-phenyl)-1-...) Show SMILES CCCCN(CCCC)c1cc(C)nc2c(nn(CC)c12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C23H30Cl2N4/c1-5-8-12-28(13-9-6-2)20-14-16(4)26-22-21(27-29(7-3)23(20)22)18-11-10-17(24)15-19(18)25/h10-11,14-15H,5-9,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	2.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity to the human corticotropin releasing factor receptor 1 expressed in HEK273 cells				Bioorg Med Chem Lett 13: 3367-70 (2003) BindingDB Entry DOI: 10.7270/Q2542N05
					More data for this Ligand-Target Pair