BDBM50132952 CHEMBL325430::[8-(2,4-Dichloro-phenyl)-2-methyl-quinolin-4-yl]-bis-(2-methoxy-ethyl)-amine

SMILES: COCCN(CCOC)c1cc(C)nc2c(cccc12)-c1ccc(Cl)cc1Cl

InChI Key: InChIKey=ZJOLQNGRAXKVOK-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50132952   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132952 (CHEMBL325430 | [8-(2,4-Dichloro-phenyl)-2-methyl-q...) Show SMILES COCCN(CCOC)c1cc(C)nc2c(cccc12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H24Cl2N2O2/c1-15-13-21(26(9-11-27-2)10-12-28-3)19-6-4-5-18(22(19)25-15)17-8-7-16(23)14-20(17)24/h4-8,13-14H,9-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	5.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligand				Bioorg Med Chem Lett 13: 3375-9 (2003) BindingDB Entry DOI: 10.7270/Q2WM1CS4
					More data for this Ligand-Target Pair
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132952 (CHEMBL325430 | [8-(2,4-Dichloro-phenyl)-2-methyl-q...) Show SMILES COCCN(CCOC)c1cc(C)nc2c(cccc12)-c1ccc(Cl)cc1Cl Show InChI InChI=1S/C22H24Cl2N2O2/c1-15-13-21(26(9-11-27-2)10-12-28-3)19-6-4-5-18(22(19)25-15)17-8-7-16(23)14-20(17)24/h4-8,13-14H,9-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Inhibition of Corticotropin releasing factor receptor 1-stimulated cAMP production				Bioorg Med Chem Lett 13: 3375-9 (2003) BindingDB Entry DOI: 10.7270/Q2WM1CS4
					More data for this Ligand-Target Pair