BDBM50132960 4-Chloro-8-(2,4-dichloro-phenyl)-2-methyl-quinoline::CHEMBL115119
SMILES: Cc1cc(Cl)c2cccc(-c3ccc(Cl)cc3Cl)c2n1
InChI Key: InChIKey=BBNQCAXGODUUPF-UHFFFAOYSA-N
Data: 1 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Corticotropin releasing factor receptor 1 (Homo sapiens (Human)) | BDBM50132960 (4-Chloro-8-(2,4-dichloro-phenyl)-2-methyl-quinolin...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Neurocrine Biosciences, Inc. Curated by ChEMBL | Assay Description Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligand | Bioorg Med Chem Lett 13: 3375-9 (2003) BindingDB Entry DOI: 10.7270/Q2WM1CS4 | |||||||||||
More data for this Ligand-Target Pair |