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BDBM50132974 CHEMBL326722::[8-(2,4-Dimethoxy-phenyl)-2-methyl-quinolin-4-yl]-dipropyl-amine

SMILES: CCCN(CCC)c1cc(C)nc2c(cccc12)-c1ccc(OC)cc1OC

InChI Key: InChIKey=NSVXDUOFUGHLQP-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132974   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Corticotropin releasing factor receptor 1


(Homo sapiens (Human))		BDBM50132974
PNG
(CHEMBL326722 | [8-(2,4-Dimethoxy-phenyl)-2-methyl-...)
Show SMILES CCCN(CCC)c1cc(C)nc2c(cccc12)-c1ccc(OC)cc1OC
Show InChI InChI=1S/C24H30N2O2/c1-6-13-26(14-7-2)22-15-17(3)25-24-20(9-8-10-21(22)24)19-12-11-18(27-4)16-23(19)28-5/h8-12,15-16H,6-7,13-14H2,1-5H3
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PubMed
 15n/an/an/an/an/an/an/an/a



Neurocrine Biosciences, Inc.

Curated by ChEMBL


Assay Description
Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligand

Bioorg Med Chem Lett 13: 3375-9 (2003)


BindingDB Entry DOI: 10.7270/Q2WM1CS4
More data for this
Ligand-Target Pair