BDBM50132975 CHEMBL114419::[8-(4-Chloro-phenyl)-2-methyl-quinolin-4-yl]-dipropyl-amine

SMILES: CCCN(CCC)c1cc(C)nc2c(cccc12)-c1ccc(Cl)cc1

InChI Key: InChIKey=JBZGTVHEOXDXKQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50132975   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Corticotropin releasing factor receptor 1 (Homo sapiens (Human))	BDBM50132975 (CHEMBL114419 | [8-(4-Chloro-phenyl)-2-methyl-quino...) Show SMILES CCCN(CCC)c1cc(C)nc2c(cccc12)-c1ccc(Cl)cc1 Show InChI InChI=1S/C22H25ClN2/c1-4-13-25(14-5-2)21-15-16(3)24-22-19(7-6-8-20(21)22)17-9-11-18(23)12-10-17/h6-12,15H,4-5,13-14H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	8.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences, Inc. Curated by ChEMBL					Assay Description Binding affinity towards cloned human Corticotropin releasing factor receptor 1 expressed in CHO cells using [125I]-o-CRF as the radioligand				Bioorg Med Chem Lett 13: 3375-9 (2003) BindingDB Entry DOI: 10.7270/Q2WM1CS4
					More data for this Ligand-Target Pair