BDBM50133226 15-methoxy-3-methyl-19-(1-methylbutyl)-13-oxa-3-azahexacyclo[13.2.2.12,8.01,6.06,14.07,12]icosa-7,9,11,16-tetraene::CHEMBL133836
SMILES: CCC[C@H](C)C1C[C@]23C=C[C@]1(OC)[C@@H]1Oc4cccc5C[C@H]2N(C)CC[C@@]31c45
InChI Key: InChIKey=ZWGNEGKIHHCRAQ-XMFPHNBZSA-N
Data: 3 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Rattus norvegicus (rat)) | BDBM50133226 (15-methoxy-3-methyl-19-(1-methylbutyl)-13-oxa-3-az...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Binding affinity against Opioid receptor kappa 1 isolated from rat brain membarane was determined using [3H]U-69593 as radioligand | J Med Chem 46: 4182-7 (2003) Article DOI: 10.1021/jm030878b BindingDB Entry DOI: 10.7270/Q22V2GVM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Rattus norvegicus (rat)) | BDBM50133226 (15-methoxy-3-methyl-19-(1-methylbutyl)-13-oxa-3-az...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Binding affinity against Opioid receptor mu 1 isolated from rat brain membarane was determined using [3H]DAMGO as radioligand | J Med Chem 46: 4182-7 (2003) Article DOI: 10.1021/jm030878b BindingDB Entry DOI: 10.7270/Q22V2GVM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Opioid receptors; mu & delta (Rattus norvegicus (rat)) | BDBM50133226 (15-methoxy-3-methyl-19-(1-methylbutyl)-13-oxa-3-az...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Innsbruck Curated by ChEMBL | Assay Description Binding affinity against Opioid receptor delta 1 isolated from rat brain membarane was determined using [3H][Ile]-deltorphin as radioligand | J Med Chem 46: 4182-7 (2003) Article DOI: 10.1021/jm030878b BindingDB Entry DOI: 10.7270/Q22V2GVM | |||||||||||
More data for this Ligand-Target Pair |