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BDBM50133237 CHEMBL133777::Nonanoic acid 4-((2S,4R)-2-hydroxymethyl-4-isopropyl-5-oxo-pyrrolidin-3-yl)-naphthalen-1-yl ester

SMILES: CCCCCCCCC(=O)Oc1ccc(C2[C@@H](CO)NC(=O)[C@@H]2C(C)C)c2ccccc12

InChI Key: InChIKey=PDWIIPAKZFCLHW-NQXVELOOSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133237   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Protein Kinase C, alpha


(Bos taurus (bovine))
BDBM50133237
PNG
(CHEMBL133777 | Nonanoic acid 4-((2S,4R)-2-hydroxym...)
Show SMILES CCCCCCCCC(=O)Oc1ccc(C2[C@@H](CO)NC(=O)[C@@H]2C(C)C)c2ccccc12
Show InChI InChI=1S/C27H37NO4/c1-4-5-6-7-8-9-14-24(30)32-23-16-15-21(19-12-10-11-13-20(19)23)26-22(17-29)28-27(31)25(26)18(2)3/h10-13,15-16,18,22,25-26,29H,4-9,14,17H2,1-3H3,(H,28,31)/t22-,25-,26?/m1/s1
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PC cid
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Article
PubMed
296n/an/an/an/an/an/an/an/a



Georgetown University Medical Center

Curated by ChEMBL


Assay Description
Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]


J Med Chem 46: 4196-204 (2003)


Article DOI: 10.1021/jm0302041
BindingDB Entry DOI: 10.7270/Q2GF0SX2
More data for this
Ligand-Target Pair