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BDBM50133251 CHEMBL336963::Tetradecanedioic acid 4-(2-hydroxymethyl-4-isopropyl-5-oxo-pyrrolidin-3-yl)-naphthalen-1-yl ester naphthalen 4-(2-hydroxymethyl-4-isopropyl-5-oxo-pyrrolidin-3-yl)-1-yl ester

SMILES: CC(C)[C@@H]1C([C@@H](CO)NC1=O)c1ccc(OC(=O)CCCCCCCCCCCCC(=O)Oc2ccc([C@@H]3[C@@H](CO)NC(=O)[C@@H]3C(C)C)c3ccccc23)c2ccccc12

InChI Key: InChIKey=JOQGMLCUDWVQRM-MASUEJKISA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133251   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Protein Kinase C, alpha


(Bos taurus (bovine))		BDBM50133251
PNG
(CHEMBL336963 | Tetradecanedioic acid 4-(2-hydroxym...)
Show SMILES CC(C)[C@@H]1C([C@@H](CO)NC1=O)c1ccc(OC(=O)CCCCCCCCCCCCC(=O)Oc2ccc([C@@H]3[C@@H](CO)NC(=O)[C@@H]3C(C)C)c3ccccc23)c2ccccc12
Show InChI InChI=1S/C50H64N2O8/c1-31(2)45-47(39(29-53)51-49(45)57)37-25-27-41(35-21-17-15-19-33(35)37)59-43(55)23-13-11-9-7-5-6-8-10-12-14-24-44(56)60-42-28-26-38(34-20-16-18-22-36(34)42)48-40(30-54)52-50(58)46(48)32(3)4/h15-22,25-28,31-32,39-40,45-48,53-54H,5-14,23-24,29-30H2,1-4H3,(H,51,57)(H,52,58)/t39-,40-,45-,46-,47-,48?/m1/s1
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Article
PubMed
 154n/an/an/an/an/an/an/an/a



Georgetown University Medical Center

Curated by ChEMBL


Assay Description
Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]

J Med Chem 46: 4196-204 (2003)


Article DOI: 10.1021/jm0302041
BindingDB Entry DOI: 10.7270/Q2GF0SX2
More data for this
Ligand-Target Pair