BindingDB logo
myBDB logout

BDBM50133288 CHEMBL3634934

SMILES: OC(=O)c1ccc(O)c2nc(ccc12)C(=O)Nc1cccc2ccccc12

InChI Key: InChIKey=KIFWIALMBKLQDD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133288   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Lysine-specific demethylase 4A (KDM4A)


(Homo sapiens (Human))		BDBM50133288
PNG
(CHEMBL3634934)
Show SMILES OC(=O)c1ccc(O)c2nc(ccc12)C(=O)Nc1cccc2ccccc12
Show InChI InChI=1S/C21H14N2O4/c24-18-11-9-15(21(26)27)14-8-10-17(22-19(14)18)20(25)23-16-7-3-5-12-4-1-2-6-13(12)16/h1-11,24H,(H,23,25)(H,26,27)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
PubMed
n/an/a>1.00E+5n/an/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Inhibition of recombinant human JMJD2A using biotinylated histone H3 as substrate by AlphaScreen assay

Eur J Med Chem 105: 145-55 (2015)


BindingDB Entry DOI: 10.7270/Q2ZG6V2N
More data for this
Ligand-Target Pair