BDBM50133444 4-(2-Chloro-phenyl)-1-ethyl-5-isopropylcarbamoyl-6-methyl-1,4-dihydro-pyridine-2,3-dicarboxylic acid::CHEMBL114226

SMILES: CCN1C(C)=C(C(C(C(O)=O)=C1C(O)=O)c1ccccc1Cl)C(=O)NC(C)C

InChI Key: InChIKey=OAVAPCQUXMEVTP-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50133444   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Muscle glycogen phosphorylase (Homo sapiens (Human))	BDBM50133444 (4-(2-Chloro-phenyl)-1-ethyl-5-isopropylcarbamoyl-6...) Show SMILES CCN1C(C)=C(C(C(C(O)=O)=C1C(O)=O)c1ccccc1Cl)C(=O)NC(C)C |c:4,10| Show InChI InChI=1S/C20H23ClN2O5/c1-5-23-11(4)14(18(24)22-10(2)3)15(12-8-6-7-9-13(12)21)16(19(25)26)17(23)20(27)28/h6-10,15H,5H2,1-4H3,(H,22,24)(H,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	12.9	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against human muscle glycogen phosphorylase a (HMGPa)				Bioorg Med Chem Lett 13: 3405-8 (2003) BindingDB Entry DOI: 10.7270/Q2TQ60XP
					More data for this Ligand-Target Pair
Glycogen Phosphorylase (PYGL) (Homo sapiens (Human))	BDBM50133444 (4-(2-Chloro-phenyl)-1-ethyl-5-isopropylcarbamoyl-6...) Show SMILES CCN1C(C)=C(C(C(C(O)=O)=C1C(O)=O)c1ccccc1Cl)C(=O)NC(C)C |c:4,10| Show InChI InChI=1S/C20H23ClN2O5/c1-5-23-11(4)14(18(24)22-10(2)3)15(12-8-6-7-9-13(12)21)16(19(25)26)17(23)20(27)28/h6-10,15H,5H2,1-4H3,(H,22,24)(H,25,26)(H,27,28)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	9.10	n/a	n/a	n/a	n/a	n/a	n/a
Merck Research Laboratories Curated by ChEMBL					Assay Description In vitro inhibitory activity against human liver glycogen phosphorylase a (HLGPa)				Bioorg Med Chem Lett 13: 3405-8 (2003) BindingDB Entry DOI: 10.7270/Q2TQ60XP
					More data for this Ligand-Target Pair