BDBM50133709 CHEMBL3633683

SMILES: CC12CC3CC(C)(C1)CC(C3)(C2)NC(=O)NCc1cc(no1)-c1cccc(F)c1

InChI Key: InChIKey=CVLZTENRROIXAR-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133709   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
EBifunctional epoxide hydrolase 2 (Homo sapiens (Human))	BDBM50133709 (CHEMBL3633683) Show SMILES CC12CC3CC(C)(C1)CC(C3)(C2)NC(=O)NCc1cc(no1)-c1cccc(F)c1 |TLB:4:5:11:3.2.10,4:3:11:7.5.8,6:5:11:3.2.10,6:5:1.11.2:10,7:1:5.8.4:10,THB:0:1:5.8.4:10,7:5:1.11.2:10| Show InChI InChI=1S/C23H28FN3O2/c1-21-8-15-9-22(2,12-21)14-23(10-15,13-21)26-20(28)25-11-18-7-19(27-29-18)16-4-3-5-17(24)6-16/h3-7,15H,8-14H2,1-2H3,(H2,25,26,28)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
University of California at Davis Curated by ChEMBL					Assay Description Inhibition of recombinant human soluble epoxide hydrolase using CMNPC as substrate by kinetic fluorescent assay				Bioorg Med Chem Lett 25: 5514-9 (2015) BindingDB Entry DOI: 10.7270/Q28P62C1
					More data for this Ligand-Target Pair