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SMILES: Cn1cc(C#N)c2ccc(Nc3ncc(o3)-c3ccccc3)cc12

InChI Key: InChIKey=LBJPVPNHTJAPJX-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50133728   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Inosine-5'-monophosphate dehydrogenase 2


(Homo sapiens (Human))		BDBM50133728
PNG
(1-Methyl-6-(5-phenyl-oxazol-2-ylamino)-1H-indole-3...)
Show SMILES Cn1cc(C#N)c2ccc(Nc3ncc(o3)-c3ccccc3)cc12
Show InChI InChI=1S/C19H14N4O/c1-23-12-14(10-20)16-8-7-15(9-17(16)23)22-19-21-11-18(24-19)13-5-3-2-4-6-13/h2-9,11-12H,1H3,(H,21,22)
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n/an/a 33n/an/an/an/an/an/a



Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL


Assay Description
Inhibitory activity tested against inosine-5'-monophosphate dehydrogenase 2 (IMPDH-II) enzyme

Bioorg Med Chem Lett 13: 3557-60 (2003)


BindingDB Entry DOI: 10.7270/Q2J67G94
More data for this
Ligand-Target Pair