BindingDB logo
myBDB logout

null

SMILES: COC(=O)[C@H]1CCCN1C(=O)c1cccc(c1)C(=O)N1CCC[C@H]1C(=O)C1CCCC1

InChI Key: InChIKey=VXSHJWVNCUAPKN-VQTJNVASSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134177   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolyl endopeptidase


(Sus scrofa)		BDBM50134177
PNG
((R)-1-[3-((S)-2-Cyclopentanecarbonyl-pyrrolidine-1...)
Show SMILES COC(=O)[C@H]1CCCN1C(=O)c1cccc(c1)C(=O)N1CCC[C@H]1C(=O)C1CCCC1
Show InChI InChI=1S/C24H30N2O5/c1-31-24(30)20-12-6-14-26(20)23(29)18-10-4-9-17(15-18)22(28)25-13-5-11-19(25)21(27)16-7-2-3-8-16/h4,9-10,15-16,19-20H,2-3,5-8,11-14H2,1H3/t19-,20+/m0/s1
PDB

KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 640n/an/an/an/an/an/a



University of Kuopio

Curated by ChEMBL


Assay Description
In vitro inhibition of prolyl oligopeptidase (POP) from pig brain

J Med Chem 46: 4543-51 (2003)


Article DOI: 10.1021/jm030811o
BindingDB Entry DOI: 10.7270/Q2H70F6R
More data for this
Ligand-Target Pair