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BDBM50134202 CHEMBL424175

SMILES: [O-][N+](=O)c1ccc2-c3ccc(cc3C(=O)c2c1)[N+]([O-])=O

InChI Key: InChIKey=HDVGAFBXTXDYIB-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50134202   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Urea transporter A1 (UT-A1)


(Rattus norvegicus (Rat))		BDBM50134202
PNG
(CHEMBL424175)
Show SMILES [O-][N+](=O)c1ccc2-c3ccc(cc3C(=O)c2c1)[N+]([O-])=O
Show InChI InChI=1S/C13H6N2O5/c16-13-11-5-7(14(17)18)1-3-9(11)10-4-2-8(15(19)20)6-12(10)13/h1-6H
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PubMed
n/an/a>5.00E+4n/an/an/an/an/an/a



University of California

Curated by ChEMBL


Assay Description
Inhibition of rat UT-A1 expressed in MDCK-UT-A1-AQP1-YFP cells after 15 mins by fluorescence assay

Medchemcomm 6: 1278-1284 (2015)


BindingDB Entry DOI: 10.7270/Q2QR4ZZC
More data for this
Ligand-Target Pair